Across TCGA cell cohorts, DPF3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible DPF3-associated genes across cancer lineages are RXFP2, GALNTL5, and CSH1. Each is linked with DPF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPF3-to-partner and partner-to-DPF3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPF3→partner) and Y-score (partner→DPF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	RXFP2 →	+0.051	+3.544	<.001	.009	3	2
LUNG_NSCLC_LUAD	GALNTL5 →	+0.062	+3.544	<.001	.009	3	1
LUNG_NSCLC_LUAD	CSH1 →	+0.061	+4.343	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR6C70 →	+0.292	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	LILRA5 →	+0.030	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.013	+4.078	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

DPF3 survival (RNA) · tumor vs normal (RNA) · all DPF3 data types