DPF2

Across TCGA pan-cancer cohorts, DPF2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DPF2 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DPF2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DPF2 expression acts as an unfavorable survival marker, although some lineages such as COAD and GBM show a favorable association.

COAD, HNSC, and UCEC are the cancer types where DPF2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.919	.013	24	view →
HNSC	DFS	Median	IV	0.530	0.842	.004	14	view →
UCEC	OS	Quartile	All	0.833	1.000	.015	4	view →
GBM	OS	Median	All	0.606	0.262	.009	3	view →
LUAD	DFS	Tertile	II,III,IV	0.706	0.151	.010	2	view →
CCRCC	OS	Quartile	All	0.914	1.000	.032	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DPF2–COAD (DFS)

Open the COAD breakdown →