DPEP3

Across TCGA cell cohorts, DPEP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 239 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible DPEP3-associated GO terms across cancer lineages are Renal system process, Negative regulation of cholesterol metabolic process, and Regulation of aggrephagy. Each is linked with DPEP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPEP3-to-partner and partner-to-DPEP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Renal system process grouped by DPEP3-low versus DPEP3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPEP3→partner) and Y-score (partner→DPEP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Renal system process →	-0.102	-0.004	.001	.005	3	3
BLOOD_Myeloma	Negative regulation of cholesterol metabolic process →	+0.098	+0.632	.001	.002	2	3
BLOOD_Lymphoma	Regulation of aggrephagy →	+0.099	+0.077	<.001	<.001	2	3
BLOOD_Lymphoma	Positive regulation of aggrephagy →	+0.106	+0.058	<.001	.001	2	3
LUNG_NSCLC_LUSC	Endosomal transport →	+0.037	+0.004	.004	.002	3	2
LUNG_NSCLC_LUSC	Prostaglandin catabolic process →	-0.169	-0.007	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 239 associations by consensus.

Renal system process by DPEP3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →