DPEP2

Across TCGA patient cohorts, DPEP2 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPEP2-associated genes across cancer lineages are Chondrocytes, CD8+ naive T-cells, and Adipocytes. Each is linked with DPEP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPEP2-to-partner and partner-to-DPEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondrocytes grouped by DPEP2-low versus DPEP2-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPEP2→partner) and Y-score (partner→DPEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Chondrocytes →	+0.008	+5.914	<.001	.024	3	2
UCEC	CD8+ naive T-cells →	+0.032	+3.202	.003	.009	3	2
UCEC	Adipocytes →	+0.017	+1.403	.023	.047	3	1
UCEC	Endothelial cells →	-0.031	-1.764	.045	.028	3	1
UCEC	lymphatic Endothelial cells →	-0.020	-3.138	.039	.019	3	1
UCEC	Basophils →	+0.171	+2.115	.014	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Chondrocytes by DPEP2 expression — LIHC

Explore this box plot interactively →