DPEP2

Across TCGA cell cohorts, DPEP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,635 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DPEP2-associated GO terms across cancer lineages are Leukotriene D4 catabolic process, Regulation of hydrolase activity, and Respiratory tube development. Each is linked with DPEP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both DPEP2-to-partner and partner-to-DPEP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukotriene D4 catabolic process grouped by DPEP2-low versus DPEP2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPEP2→partner) and Y-score (partner→DPEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Leukotriene D4 catabolic process →	+0.725	+1.315	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of hydrolase activity →	+0.065	+0.247	<.001	.005	3	5
UPPER_AERODIGESTIVE_TRACT	Respiratory tube development →	+0.053	+0.180	.009	.003	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of protein polymerization →	+0.094	+0.227	<.001	.006	3	5
BLOOD_Leukemia	Homologous chromosome segregation →	-0.080	-1.240	.001	<.001	3	5
BLOOD_Leukemia	Positive regulation of pattern recognition receptor signaling pathway →	+0.021	+0.635	.002	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,635 associations by consensus.

Leukotriene D4 catabolic process by DPEP2 expression — BLOOD_Leukemia

Explore this box plot interactively →