DPEP1

Across TCGA pan-cancer cohorts, DPEP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated DPEP1 data layer compared with 20 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher DPEP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DPEP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

LUAD, CCRCC, and GBM are the cancer types where DPEP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.831	0.307	<.001	19	view →
CCRCC	DFS	Tertile	All	0.964	0.619	.002	19	view →
GBM	OS	Median	All	0.648	0.876	.035	2	view →
PDAC	OS	Quartile	III,IV	0.977	0.545	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DPEP1–LUAD (DFS)

Open the LUAD breakdown →