DPEP1

Across TCGA patient cohorts, DPEP1 mutation is significantly associated with the RNA expression of many other genes, with 259 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPEP1-associated genes across cancer lineages are OR7E37P, MIR6826, and OR4D1. Each is linked with DPEP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both DPEP1-to-partner and partner-to-DPEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7E37P grouped by DPEP1-low versus DPEP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPEP1→partner) and Y-score (partner→DPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR7E37P →	+0.063	+2.848	<.001	.004	3	3
BRCA	MIR6826 →	+0.791	+4.264	<.001	.003	3	2
BRCA	OR4D1 →	+0.052	+5.197	<.001	<.001	3	2
BRCA	RNA5SP97 →	+0.547	+4.536	<.001	.001	3	2
UCEC	FKBP4P2 →	+0.021	+2.602	.007	.006	3	2
SARC	SNORD105B →	+0.851	+5.005	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

OR7E37P by DPEP1 expression — SKCM

Explore this box plot interactively →