DPEP1

Across TCGA patient cohorts, DPEP1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPEP1-associated genes across cancer lineages are Neutrophils, Astrocytes, and pDC. Each is linked with DPEP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPEP1-to-partner and partner-to-DPEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Neutrophils grouped by DPEP1-low versus DPEP1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPEP1→partner) and Y-score (partner→DPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Neutrophils →	+0.005	+2.612	.030	.034	3	2
LUAD	Astrocytes →	+0.075	+2.500	.003	.042	3	1
UCEC	pDC →	+0.044	+3.032	.037	.018	3	1
UCEC	Sebocytes →	-0.024	-2.094	.028	.019	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Neutrophils by DPEP1 expression — LUAD

Explore this box plot interactively →