DPEP1

Across TCGA cell cohorts, DPEP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,079 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DPEP1-associated GO terms across cancer lineages are Leukotriene D4 catabolic process, Leukotriene catabolic process, and Regulation of plasminogen activation. Each is linked with DPEP1 in more than 15 cancer types. Because this analysis shows association rather than direction, both DPEP1-to-partner and partner-to-DPEP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Leukotriene D4 catabolic process grouped by DPEP1-low versus DPEP1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DPEP1→partner) and Y-score (partner→DPEP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Leukotriene D4 catabolic process →	+2.167	+5.698	<.001	<.001	3	16
LARGE_INTESTINE	Leukotriene catabolic process →	+1.584	+4.840	<.001	<.001	3	8
BONE	Regulation of plasminogen activation →	-0.264	-1.481	<.001	.001	3	6
STOMACH	Blood coagulation, fibrin clot formation →	-0.316	-1.693	<.001	.001	3	6
LARGE_INTESTINE	Regulation of mesonephros development →	-0.727	-3.312	<.001	<.001	3	5
LARGE_INTESTINE	Regulation of ureteric bud formation →	-0.727	-3.312	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,079 associations by consensus.

Leukotriene D4 catabolic process by DPEP1 expression — LARGE_INTESTINE

Explore this box plot interactively →