DPCD

Across TCGA patient cohorts, DPCD protein abundance is significantly associated with the RNA expression of many other genes, with 9,001 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DPCD-associated genes across cancer lineages are MRPL43, SPEF1, and RSPH1. Each is linked with DPCD in more than 6 cancer types. Because this analysis shows association rather than direction, both DPCD-to-partner and partner-to-DPCD results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DPCD versus MRPL43 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPCD→partner) and Y-score (partner→DPCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MRPL43 →	+0.522	+0.515	<.001	.001	3	7
UCEC	SPEF1 →	+1.258	+0.348	<.001	<.001	3	6
GBM	RSPH1 →	+1.424	+0.485	<.001	<.001	3	6
UCEC	EFCAB12 →	+0.923	+0.547	<.001	<.001	3	6
UCEC	FANK1 →	+1.125	+0.528	<.001	<.001	3	6
UCEC	IFT22 →	+0.758	+0.610	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,001 associations by consensus.

DPCD vs MRPL43 — OV

Explore this scatter interactively →