DPCD

Across TCGA patient cohorts, DPCD mutation is significantly associated with the RNA expression of many other genes, with 58 significant associations in total. COAD shows the largest number of these associations.

The most reproducible DPCD-associated genes across cancer lineages are MIR6855, H2BC3, and RNVU1-28. Each is linked with DPCD in more than 1 cancer types. Because this analysis shows association rather than direction, both DPCD-to-partner and partner-to-DPCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6855 grouped by DPCD-low versus DPCD-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPCD→partner) and Y-score (partner→DPCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6855 →	+0.915	+2.839	<.001	.004	3	1
UCEC	H2BC3 →	+0.406	+3.432	.007	.009	3	1
UCEC	RNVU1-28 →	+0.982	+2.635	<.001	.008	3	1
UCEC	RNA5SP382 →	+0.750	+3.029	<.001	.005	3	1
UCEC	RNU6-1180P →	+0.217	+4.069	<.001	.008	3	1
UCEC	AWAT1 →	+0.446	+3.823	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 58 associations by consensus.

MIR6855 by DPCD expression — UCEC

Explore this box plot interactively →