DPCD

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DPCD mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPCD-associated genes across cancer lineages are Monocytes and CD8+ Tem. Each is linked with DPCD in more than 1 cancer types. Because this analysis shows association rather than direction, both DPCD-to-partner and partner-to-DPCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by DPCD-low versus DPCD-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPCD→partner) and Y-score (partner→DPCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCMonocytes →+0.017+5.273.026.00631
UCECCD8+ Tem →+0.004+5.066<.001.03331
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Monocytes by DPCD expression — LUSC

Box plot of Monocytes in DPCD-low vs DPCD-high samples in LUSC.

Explore this box plot interactively →

Exploration