DPCD

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DPCD mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPCD-associated genes across cancer lineages are OR10W1. Each is linked with DPCD in more than 1 cancer types. Because this analysis shows association rather than direction, both DPCD-to-partner and partner-to-DPCD results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by DPCD-low versus DPCD-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPCD→partner) and Y-score (partner→DPCD) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR10W1 →+0.019+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

OR10W1 by DPCD expression — LARGE_INTESTINE

Box plot of OR10W1 in DPCD-low vs DPCD-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration