DPAGT1

Across TCGA pan-cancer cohorts, DPAGT1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DPAGT1 data layer compared with 28 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DPAGT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated DPAGT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

CCRCC, LUAD, and HNSC are the cancer types where DPAGT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.431	0.857	.006	9	view →
LUAD	DFS	Median	All	0.885	1.000	.013	5	view →
HNSC	OS	Quartile	II,III,IV	0.942	0.819	.043	2	view →
PDAC	OS	Quartile	All	0.479	0.693	.021	2	view →
LSCC	OS	Tertile	III,IV	0.921	0.569	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DPAGT1–CCRCC (DFS)

Open the CCRCC breakdown →