DOP1B

Across TCGA patient cohorts, DOP1B protein abundance is significantly associated with the RNA expression of many other genes, with 12,306 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DOP1B-associated genes across cancer lineages are MLPH, SLC37A1, and BCAS1. Each is linked with DOP1B in more than 6 cancer types. Because this analysis shows association rather than direction, both DOP1B-to-partner and partner-to-DOP1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOP1B versus MLPH in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOP1B→partner) and Y-score (partner→DOP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MLPH →	+2.969	+0.449	<.001	<.001	3	7
BRCA	SLC37A1 →	+0.682	+0.333	<.001	<.001	3	6
LUAD	BCAS1 →	+2.051	+0.271	<.001	<.001	3	6
BRCA	SRSF9P1 →	+0.571	+0.307	<.001	<.001	3	6
UCEC	ELAPOR1 →	+2.304	+0.285	<.001	.002	3	5
BRCA	MISP3 →	+0.979	+0.266	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,306 associations by consensus.

DOP1B vs MLPH — BRCA

Explore this scatter interactively →