DOP1B

Across TCGA cell cohorts, DOP1B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,440 significant associations in total. CNS shows the largest number of these associations.

The most reproducible DOP1B-associated GO terms across cancer lineages are Golgi to endosome transport, Cytosolic transport, and Vesicle-mediated transport to the plasma membrane. Each is linked with DOP1B in more than 15 cancer types. Because this analysis shows association rather than direction, both DOP1B-to-partner and partner-to-DOP1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to endosome transport grouped by DOP1B-low versus DOP1B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOP1B→partner) and Y-score (partner→DOP1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Golgi to endosome transport →	+0.146	+1.249	.001	.005	3	16
STOMACH	Cytosolic transport →	+0.065	+1.284	.001	.001	3	15
SOFT_TISSUE	Vesicle-mediated transport to the plasma membrane →	+0.064	+1.180	<.001	<.001	3	14
BONE	Post-Golgi vesicle-mediated transport →	+0.069	+1.266	.001	.001	3	14
SOFT_TISSUE	Endosomal transport →	+0.060	+1.160	<.001	<.001	3	13
URINARY_TRACT	Endocytic recycling →	+0.063	+1.254	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,440 associations by consensus.

Golgi to endosome transport by DOP1B expression — STOMACH

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