DOK7

Across TCGA patient cohorts, DOK7 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,274 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DOK7-associated proteins across cancer lineages are DOK7_S419, MYEF2, and TNKS1BP1_S691. Each is linked with DOK7 in more than 4 cancer types. Because this analysis shows association rather than direction, both DOK7-to-partner and partner-to-DOK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK7 versus DOK7_S419 in BRCA, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK7→partner) and Y-score (partner→DOK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DOK7_S419 →	+1.108	+1.443	<.001	<.001	3	5
HNSC	MYEF2 →	+0.564	+0.425	<.001	.001	3	4
BRCA	TNKS1BP1_S691 →	-0.685	-1.382	<.001	<.001	3	3
OV	PYGL →	-0.393	-1.034	.004	.007	3	3
BRCA	RACK1 →	-0.157	-1.095	<.001	.004	3	3
OV	MRE11 →	+0.337	+1.190	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,274 associations by consensus.

DOK7 vs DOK7_S419 — BRCA

Explore this scatter interactively →