DOK7

Across TCGA patient cohorts, DOK7 protein abundance is significantly associated with the RNA expression of many other genes, with 1,745 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DOK7-associated genes across cancer lineages are HOXB9, TRBV10-3, and TLE1. Each is linked with DOK7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DOK7-to-partner and partner-to-DOK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK7 versus HOXB9 in OV, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK7→partner) and Y-score (partner→DOK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HOXB9 →	-1.771	-1.023	.002	<.001	3	2
BRCA	TRBV10-3 →	-1.074	-0.870	<.001	<.001	3	2
BRCA	TLE1 →	-0.943	-0.587	.002	.005	3	2
OV	DNAJA3 →	+0.342	+0.571	.007	.003	3	1
OV	CNFN →	-1.322	-0.934	<.001	<.001	3	1
OV	PTGDS →	-1.425	-0.686	.004	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,745 associations by consensus.

DOK7 vs HOXB9 — OV

Explore this scatter interactively →