DOK5

Across TCGA patient cohorts, DOK5 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,774 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOK5-associated proteins across cancer lineages are CNN3, TUBB6, and PRKD1. Each is linked with DOK5 in more than 6 cancer types. Because this analysis shows association rather than direction, both DOK5-to-partner and partner-to-DOK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK5 versus CNN3 in BRCA, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK5→partner) and Y-score (partner→DOK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNN3 →	+0.576	+0.751	<.001	<.001	3	7
UCEC	TUBB6 →	+0.423	+0.776	<.001	<.001	3	7
COAD	PRKD1 →	+0.740	+0.750	<.001	<.001	3	6
COAD	QKI →	+0.301	+0.421	<.001	<.001	3	6
LSCC	RASA3_S809 →	+0.934	+0.615	<.001	<.001	3	6
BRCA	SERPINH1 →	+0.499	+0.737	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,774 associations by consensus.

DOK5 vs CNN3 — BRCA

Explore this scatter interactively →