DOK5

Across TCGA patient cohorts, DOK5 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,201 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOK5-associated proteins across cancer lineages are ATP2B3_T1079, BIRC6_S486, and CEP170_T914. Each is linked with DOK5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DOK5-to-partner and partner-to-DOK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK5 versus ATP2B3_T1079 in GBM, with a Pearson correlation of -0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK5→partner) and Y-score (partner→DOK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ATP2B3_T1079 →	-1.586	-2.508	<.001	<.001	3	1
GBM	BIRC6_S486 →	-0.391	-1.789	.001	<.001	3	1
GBM	CEP170_T914 →	+0.813	+2.359	<.001	.002	3	1
GBM	CHRM3_S299 →	-1.026	-1.655	<.001	.002	3	1
GBM	ABCC5_S505 →	-0.812	-2.110	.002	.002	3	1
GBM	DDX60L →	+0.604	+0.419	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,201 associations by consensus.

DOK5 vs ATP2B3_T1079 — GBM

Explore this scatter interactively →