DOK3

Across TCGA patient cohorts, DOK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,160 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOK3-associated proteins across cancer lineages are RASAL3, PTPRC, and SASH3. Each is linked with DOK3 in more than 9 cancer types. Because this analysis shows association rather than direction, both DOK3-to-partner and partner-to-DOK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK3 versus RASAL3 in OV, with a Pearson correlation of 0.59.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK3→partner) and Y-score (partner→DOK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RASAL3 →	+0.680	+1.208	<.001	<.001	3	10
GBM	PTPRC →	+0.908	+0.967	<.001	<.001	3	10
UCEC	SASH3 →	+0.665	+0.811	<.001	<.001	3	10
GBM	SKAP2 →	+0.887	+0.939	<.001	<.001	3	10
LSCC	STK10 →	+0.497	+0.768	<.001	<.001	3	10
HNSC	STK4 →	+0.389	+0.650	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,160 associations by consensus.

DOK3 vs RASAL3 — OV

Explore this scatter interactively →