DOK2

Across TCGA patient cohorts, DOK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,359 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOK2-associated proteins across cancer lineages are MYO1G, NCF2, and NCF4. Each is linked with DOK2 in more than 9 cancer types. Because this analysis shows association rather than direction, both DOK2-to-partner and partner-to-DOK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK2 versus MYO1G in GBM, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK2→partner) and Y-score (partner→DOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MYO1G →	+0.797	+1.373	<.001	<.001	3	10
GBM	NCF2 →	+0.958	+1.303	<.001	<.001	3	10
GBM	NCF4 →	+0.913	+1.420	<.001	<.001	3	10
OV	NECAP2 →	+0.353	+1.122	<.001	<.001	3	10
OV	ARHGAP25 →	+1.445	+1.989	.002	<.001	3	10
OV	ARHGAP30 →	+0.789	+1.287	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,359 associations by consensus.

DOK2 vs MYO1G — GBM

Explore this scatter interactively →