DOK1

Across TCGA patient cohorts, DOK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,987 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DOK1-associated proteins across cancer lineages are DOK1_S269, SAMHD1, and DOCK10. Each is linked with DOK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both DOK1-to-partner and partner-to-DOK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOK1 versus DOK1_S269 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK1→partner) and Y-score (partner→DOK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DOK1_S269 →	+0.780	+0.576	<.001	<.001	3	8
GBM	SAMHD1 →	+0.410	+0.426	<.001	<.001	3	6
CCRCC	DOCK10 →	+0.402	+0.429	<.001	<.001	3	6
HNSC	DOCK10_T1440 →	+0.658	+0.702	<.001	.002	3	6
GBM	RHOG →	+0.253	+0.292	.001	<.001	3	5
BRCA	RIPK3 →	+0.498	+0.816	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,987 associations by consensus.

DOK1 vs DOK1_S269 — OV

Explore this scatter interactively →