DOK1

Across TCGA cell cohorts, DOK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,107 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DOK1-associated GO terms across cancer lineages are Collagen biosynthetic process, Regulation of intracellular protein transport, and Exploration behavior. Each is linked with DOK1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DOK1-to-partner and partner-to-DOK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen biosynthetic process grouped by DOK1-low versus DOK1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOK1→partner) and Y-score (partner→DOK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Collagen biosynthetic process →	+0.220	+1.262	<.001	<.001	3	10
CNS	Regulation of intracellular protein transport →	+0.047	+0.976	<.001	<.001	3	9
CNS	Exploration behavior →	+0.107	+1.207	.001	.001	3	9
LUNG_NSCLC_LUSC	Skeletal muscle fiber development →	+0.196	+1.467	<.001	.001	3	9
BONE	Positive regulation of cell-substrate junction organization →	+0.199	+1.771	<.001	<.001	3	8
BONE	Regulation of cell-substrate junction organization →	+0.128	+1.115	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,107 associations by consensus.

Collagen biosynthetic process by DOK1 expression — BONE

Explore this box plot interactively →