DOCK9

Across TCGA patient cohorts, DOCK9 protein abundance is significantly associated with the RNA expression of many other genes, with 14,784 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DOCK9-associated genes across cancer lineages are DOCK9-DT, RAPGEF3, and CLN5. Each is linked with DOCK9 in more than 7 cancer types. Because this analysis shows association rather than direction, both DOCK9-to-partner and partner-to-DOCK9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK9 versus DOCK9-DT in OV, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK9→partner) and Y-score (partner→DOCK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DOCK9-DT →	+0.908	+0.509	<.001	<.001	3	8
CCRCC	RAPGEF3 →	+0.894	+0.311	<.001	<.001	3	7
BRCA	CLN5 →	+0.407	+0.246	<.001	<.001	3	6
OV	CTDSPL →	+0.574	+0.258	.006	.009	3	6
UCEC	STXBP1 →	+0.938	+0.247	<.001	<.001	3	6
CCRCC	DOCK9-AS1 →	+1.158	+0.343	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,784 associations by consensus.

DOCK9 vs DOCK9-DT — OV

Explore this scatter interactively →