DOCK9

Across TCGA cell cohorts, DOCK9 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,272 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DOCK9-associated GO terms across cancer lineages are Regulation of protein modification by small protein conjugation or removal, Positive regulation of GTPase activity, and Regulation of tumor necrosis factor-mediated signaling pathway. Each is linked with DOCK9 in more than 12 cancer types. Because this analysis shows association rather than direction, both DOCK9-to-partner and partner-to-DOCK9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein modification by small protein conjugation or removal grouped by DOCK9-low versus DOCK9-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK9→partner) and Y-score (partner→DOCK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of protein modification by small protein conjugation or removal →	+0.030	+1.704	<.001	.001	3	13
BREAST	Positive regulation of GTPase activity →	+0.061	+1.155	<.001	<.001	3	12
PANCREAS	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.090	+1.440	.001	.001	3	11
STOMACH	Endosomal transport →	+0.071	+1.474	<.001	<.001	3	11
BONE	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.123	+1.947	.003	.001	3	11
STOMACH	Regulation of Rho protein signal transduction →	+0.109	+1.375	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,272 associations by consensus.

Regulation of protein modification by small protein conjugation or removal by DOCK9 expression — BLOOD_Leukemia

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