Across TCGA pan-cancer cohorts, DOCK8-AS1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated DOCK8-AS1 data layer compared with 19 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher DOCK8-AS1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated DOCK8-AS1 expression acts as an unfavorable survival marker.

SCLC, OV, and COAD are the cancer types where DOCK8-AS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.082	0.708	<.001	36	view →
OV	DFS	Median	II,III,IV	0.204	0.541	.017	12	view →
COAD	OS	Median	All	0.113	0.806	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: DOCK8-AS1 tumor-vs-normal RNA expression · all DOCK8-AS1 data types