DOCK7

Across TCGA patient cohorts, DOCK7 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,851 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible DOCK7-associated proteins across cancer lineages are DOCK7_S1383, IRF4, and MLYCD. Each is linked with DOCK7 in more than 4 cancer types. Because this analysis shows association rather than direction, both DOCK7-to-partner and partner-to-DOCK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK7 versus DOCK7_S1383 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK7→partner) and Y-score (partner→DOCK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DOCK7_S1383 →	+0.451	+0.454	<.001	<.001	3	5
HNSC	IRF4 →	-0.851	-0.591	<.001	<.001	3	4
BRCA	MLYCD →	-0.283	-0.473	<.001	<.001	3	4
OV	SUCLG1 →	-0.411	-0.502	<.001	.008	3	4
LSCC	CTPS2 →	+0.370	+0.450	<.001	<.001	3	4
LSCC	SPCS3 →	-0.453	-0.339	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,851 associations by consensus.

DOCK7 vs DOCK7_S1383 — LSCC

Explore this scatter interactively →