DOCK7

Across TCGA patient cohorts, DOCK7 protein abundance is significantly associated with the RNA expression of many other genes, with 13,397 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK7-associated genes across cancer lineages are CD22, ETV5, and CMTM3. Each is linked with DOCK7 in more than 5 cancer types. Because this analysis shows association rather than direction, both DOCK7-to-partner and partner-to-DOCK7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK7 versus CD22 in GBM, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK7→partner) and Y-score (partner→DOCK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD22 →	-1.209	-0.287	<.001	<.001	3	6
HNSC	ETV5 →	+0.812	+0.211	<.001	<.001	3	5
PDAC	CMTM3 →	+0.747	+0.201	<.001	<.001	3	5
UCEC	VGLL4 →	+0.474	+0.131	<.001	<.001	3	5
HNSC	PSD3 →	+0.860	+0.233	<.001	<.001	3	5
BRCA	NCS1 →	+0.815	+0.210	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,397 associations by consensus.

DOCK7 vs CD22 — GBM

Explore this scatter interactively →