DOCK7

Across TCGA cell cohorts, DOCK7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,260 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible DOCK7-associated GO terms across cancer lineages are Establishment or maintenance of neuroblast polarity, Establishment of neuroblast polarity, and Septin ring organization. Each is linked with DOCK7 in more than 17 cancer types. Because this analysis shows association rather than direction, both DOCK7-to-partner and partner-to-DOCK7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of neuroblast polarity grouped by DOCK7-low versus DOCK7-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK7→partner) and Y-score (partner→DOCK7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Establishment or maintenance of neuroblast polarity →	+0.286	+1.484	<.001	<.001	3	18
URINARY_TRACT	Establishment of neuroblast polarity →	+0.286	+1.484	<.001	<.001	3	18
PANCREAS	Septin ring organization →	+0.153	+0.847	<.001	<.001	3	13
BONE	Phosphatidylinositol biosynthetic process →	+0.068	+0.980	.001	<.001	3	12
SKIN	Retrograde transport, endosome to Golgi →	+0.069	+0.820	<.001	.001	3	12
LUNG_NSCLC_LUSC	Phosphatidylinositol metabolic process →	+0.067	+1.358	.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,260 associations by consensus.

Establishment or maintenance of neuroblast polarity by DOCK7 expression — URINARY_TRACT

Explore this box plot interactively →