DOCK6

Across TCGA patient cohorts, DOCK6 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,612 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DOCK6-associated proteins across cancer lineages are NID1, DOCK6_S159, and HMCN1. Each is linked with DOCK6 in more than 4 cancer types. Because this analysis shows association rather than direction, both DOCK6-to-partner and partner-to-DOCK6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK6 versus NID1 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK6→partner) and Y-score (partner→DOCK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NID1 →	+0.522	+0.490	<.001	.002	3	5
GBM	DOCK6_S159 →	+0.602	+0.853	<.001	<.001	3	5
CCRCC	HMCN1 →	+0.606	+0.723	<.001	<.001	3	5
LUAD	TBX2_S710 →	+0.799	+0.426	<.001	<.001	3	5
GBM	LAMA4 →	+0.626	+0.569	<.001	.001	3	5
BRCA	SSC5D →	+0.720	+0.785	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,612 associations by consensus.

DOCK6 vs NID1 — BRCA

Explore this scatter interactively →