DOCK6

Across TCGA patient cohorts, DOCK6 protein abundance is significantly associated with the RNA expression of many other genes, with 12,766 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible DOCK6-associated genes across cancer lineages are LILRB1, TAGAP, and LPXN. Each is linked with DOCK6 in more than 6 cancer types. Because this analysis shows association rather than direction, both DOCK6-to-partner and partner-to-DOCK6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK6 versus LILRB1 in LSCC, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK6→partner) and Y-score (partner→DOCK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LILRB1 →	-0.692	-0.276	<.001	<.001	3	7
COAD	TAGAP →	-0.778	-0.253	<.001	<.001	3	7
UCEC	LPXN →	-0.585	-0.201	.002	.008	3	6
LSCC	IFNG →	-1.044	-0.306	<.001	<.001	3	6
COAD	IL21 →	-0.385	-0.287	<.001	<.001	3	6
CCRCC	PTPN7 →	-0.956	-0.330	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,766 associations by consensus.

DOCK6 vs LILRB1 — LSCC

Explore this scatter interactively →