DOCK5

Across TCGA patient cohorts, DOCK5 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,632 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DOCK5-associated proteins across cancer lineages are DOCK5_S1766, DOCK5_S1742, and DOCK5_S1287. Each is linked with DOCK5 in more than 8 cancer types. Because this analysis shows association rather than direction, both DOCK5-to-partner and partner-to-DOCK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK5 versus DOCK5_S1766 in GBM, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK5→partner) and Y-score (partner→DOCK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DOCK5_S1766 →	+1.032	+1.354	<.001	<.001	3	9
UCEC	DOCK5_S1742 →	+0.995	+0.955	<.001	<.001	3	8
UCEC	DOCK5_S1287 →	+1.046	+1.212	<.001	.001	3	6
OV	ARHGEF10 →	+0.451	+0.849	<.001	.001	3	6
COAD	GCA →	+0.568	+0.737	<.001	<.001	3	5
GBM	ATP6V1E1 →	+0.494	+1.064	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,632 associations by consensus.

DOCK5 vs DOCK5_S1766 — GBM

Explore this scatter interactively →