DOCK5

Across TCGA patient cohorts, DOCK5 protein abundance is significantly associated with the RNA expression of many other genes, with 13,986 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK5-associated genes across cancer lineages are TNFRSF10B, SH2D4A, and GNRH1. Each is linked with DOCK5 in more than 7 cancer types. Because this analysis shows association rather than direction, both DOCK5-to-partner and partner-to-DOCK5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK5 versus TNFRSF10B in OV, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK5→partner) and Y-score (partner→DOCK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TNFRSF10B →	+0.951	+0.357	<.001	<.001	3	8
OV	SH2D4A →	+0.758	+0.238	<.001	.004	3	6
BRCA	GNRH1 →	+0.875	+0.344	<.001	<.001	3	6
BRCA	SLC25A37 →	+0.730	+0.302	.004	.002	3	6
GBM	PLAUR →	+1.019	+0.695	.001	<.001	3	6
GBM	TNFRSF10A →	+0.807	+0.808	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,986 associations by consensus.

DOCK5 vs TNFRSF10B — OV

Explore this scatter interactively →