DOCK5

Across TCGA cell cohorts, DOCK5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,646 significant associations in total. BONE shows the largest number of these associations.

The most reproducible DOCK5-associated GO terms across cancer lineages are Positive regulation of vascular associated smooth muscle cell migration, Myelination, and Assembly of actomyosin apparatus involved in cytokinesis. Each is linked with DOCK5 in more than 12 cancer types. Because this analysis shows association rather than direction, both DOCK5-to-partner and partner-to-DOCK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of vascular associated smooth muscle cell migration grouped by DOCK5-low versus DOCK5-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK5→partner) and Y-score (partner→DOCK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Positive regulation of vascular associated smooth muscle cell migration →	+0.174	+1.377	.001	.004	3	13
BONE	Myelination →	+0.093	+1.727	<.001	<.001	3	11
BONE	Assembly of actomyosin apparatus involved in cytokinesis →	+0.234	+2.119	<.001	.003	3	11
BONE	Actomyosin contractile ring assembly →	+0.234	+2.119	<.001	.003	3	11
BLOOD_Leukemia	Skeletal myofibril assembly →	+0.534	+1.575	<.001	<.001	3	10
BONE	Positive regulation of plasma membrane repair →	+0.286	+1.866	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,646 associations by consensus.

Positive regulation of vascular associated smooth muscle cell migration by DOCK5 expression — OESOPHAGUS

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