DOCK4

Across TCGA patient cohorts, DOCK4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,031 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DOCK4-associated proteins across cancer lineages are DOCK4_T1899, DOCK4_S1700, and DPYD. Each is linked with DOCK4 in more than 8 cancer types. Because this analysis shows association rather than direction, both DOCK4-to-partner and partner-to-DOCK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK4 versus DOCK4_T1899 in PDAC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK4→partner) and Y-score (partner→DOCK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DOCK4_T1899 →	+0.402	+0.376	<.001	<.001	3	9
HNSC	DOCK4_S1700 →	+0.638	+0.834	<.001	<.001	3	8
UCEC	DPYD →	+0.543	+0.552	.001	<.001	3	7
GBM	ELMO2 →	+0.307	+0.562	<.001	<.001	3	7
GBM	PREX1 →	+0.460	+0.428	<.001	<.001	3	6
LSCC	VASH1_S313 →	+0.500	+0.597	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,031 associations by consensus.

DOCK4 vs DOCK4_T1899 — PDAC

Explore this scatter interactively →