DOCK4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, DOCK4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,574 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK4-associated genes across cancer lineages are MS4A7, ATP8B4, and LILRA1. Each is linked with DOCK4 in more than 8 cancer types. Because this analysis shows association rather than direction, both DOCK4-to-partner and partner-to-DOCK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK4 versus MS4A7 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK4→partner) and Y-score (partner→DOCK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAMS4A7 →+1.254+0.295<.001<.00139
GBMATP8B4 →+0.791+0.271<.001<.00138
GBMLILRA1 →+0.719+0.305<.001<.00138
UCECTYROBP →+0.926+0.232<.001<.00138
HNSCCXorf21 →+0.867+0.250<.001<.00138
UCECHAVCR2 →+1.013+0.315<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,574 associations by consensus.

DOCK4 vs MS4A7 — BRCA

Per-sample scatter of DOCK4 vs MS4A7 in BRCA (Pearson r = 0.41).

Explore this scatter interactively →

Exploration