DOCK4

Across TCGA patient cohorts, DOCK4 protein abundance is significantly associated with the protein abundance of many other proteins, with 19,674 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DOCK4-associated proteins across cancer lineages are DOCK4_T1899, FCER1G, and ARHGEF6. Each is linked with DOCK4 in more than 8 cancer types. Because this analysis shows association rather than direction, both DOCK4-to-partner and partner-to-DOCK4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK4 versus DOCK4_T1899 in OV, with a Pearson correlation of 0.48.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK4→partner) and Y-score (partner→DOCK4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DOCK4_T1899 →	+0.556	+0.277	<.001	.001	3	9
UCEC	FCER1G →	+1.334	+0.318	<.001	<.001	3	9
LSCC	ARHGEF6 →	+0.440	+0.336	<.001	<.001	3	8
LSCC	RIN3 →	+0.390	+0.349	<.001	<.001	3	8
BRCA	DOCK4_S1700 →	+0.539	+0.202	<.001	<.001	3	8
HNSC	DOCK8 →	+0.468	+0.287	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,674 associations by consensus.

DOCK4 vs DOCK4_T1899 — OV

Explore this scatter interactively →