DOCK3

Across TCGA patient cohorts, DOCK3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,712 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DOCK3-associated proteins across cancer lineages are RAB6B, NUCB2, and PALM_S162. Each is linked with DOCK3 in more than 3 cancer types. Because this analysis shows association rather than direction, both DOCK3-to-partner and partner-to-DOCK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK3 versus RAB6B in LSCC, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK3→partner) and Y-score (partner→DOCK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RAB6B →	+0.787	+0.670	.006	.002	3	4
LUAD	NUCB2 →	-0.465	-0.788	.003	<.001	3	4
UCEC	PALM_S162 →	+0.636	+0.727	.002	<.001	3	4
HNSC	CRMP1 →	+0.920	+0.694	<.001	<.001	3	4
GBM	PALM →	+0.689	+1.045	<.001	<.001	3	4
GBM	PALM_S116 →	+0.821	+1.129	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,712 associations by consensus.

DOCK3 vs RAB6B — LSCC

Explore this scatter interactively →