DOCK3

Across TCGA patient cohorts, DOCK3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,224 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DOCK3-associated genes across cancer lineages are TESPA1, SNRPD3, and PRODH. Each is linked with DOCK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both DOCK3-to-partner and partner-to-DOCK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DOCK3 versus TESPA1 in OV, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK3→partner) and Y-score (partner→DOCK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TESPA1 →	+0.865	+1.459	.004	.009	2	2
GBM	SNRPD3 →	+0.411	+0.317	<.001	<.001	3	1
GBM	PRODH →	+0.842	+0.284	.003	.007	3	1
GBM	SEZ6L →	+1.473	+0.248	.002	.006	3	1
GBM	SOX10 →	+1.466	+0.384	<.001	<.001	3	1
GBM	SLC16A8 →	+0.488	+0.286	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,224 associations by consensus.

DOCK3 vs TESPA1 — OV

Explore this scatter interactively →