DOCK3

Across TCGA cell cohorts, DOCK3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,977 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible DOCK3-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Protein polyubiquitination, and Regulation of myoblast fusion. Each is linked with DOCK3 in more than 10 cancer types. Because this analysis shows association rather than direction, both DOCK3-to-partner and partner-to-DOCK3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by DOCK3-low versus DOCK3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK3→partner) and Y-score (partner→DOCK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Post-Golgi vesicle-mediated transport →	+0.069	+1.312	.007	.005	3	11
CNS	Protein polyubiquitination →	+0.030	+0.789	.001	.002	3	11
KIDNEY	Regulation of myoblast fusion →	+0.088	+0.982	.001	.001	3	10
STOMACH	Regulation of macroautophagy →	+0.074	+1.760	.002	<.001	3	10
STOMACH	Cytoplasmic translation →	+0.067	+1.054	.001	.001	3	10
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.092	+1.018	.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,977 associations by consensus.

Post-Golgi vesicle-mediated transport by DOCK3 expression — BONE

Explore this box plot interactively →