DOCK2

Across TCGA cell cohorts, DOCK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,483 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DOCK2-associated GO terms across cancer lineages are Positive regulation of stress fiber assembly, Dentinogenesis, and Positive regulation of chromosome organization. Each is linked with DOCK2 in more than 11 cancer types. Because this analysis shows association rather than direction, both DOCK2-to-partner and partner-to-DOCK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stress fiber assembly grouped by DOCK2-low versus DOCK2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DOCK2→partner) and Y-score (partner→DOCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of stress fiber assembly →	+0.141	+3.179	.003	.002	3	12
OVARY	Dentinogenesis →	+1.542	+1.706	<.001	<.001	3	12
URINARY_TRACT	Positive regulation of chromosome organization →	+0.071	+1.784	<.001	<.001	3	12
STOMACH	Negative regulation of cilium assembly →	+0.073	+0.462	<.001	.002	3	12
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.106	+2.072	.001	.001	3	12
BONE	Regulation of cell-matrix adhesion →	+0.132	+2.046	.002	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,483 associations by consensus.

Positive regulation of stress fiber assembly by DOCK2 expression — LIVER

Explore this box plot interactively →