DOCK11P1

Across TCGA pan-cancer cohorts, DOCK11P1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of DOCK11P1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where DOCK11P1 RNA is repressed in tumor relative to normal tissue. In most cancer types DOCK11P1 is over-expressed in tumor, although a few such as BRCA and UCEC show the opposite, repressed pattern.

BRCA, HNSC, and UCEC are the cancer types where DOCK11P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DOCK11P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	II,III,IV	−0.009	<.001	4	view →
HNSC	All	II,III,IV	+0.003	.016	4	view →
UCEC	All	All	−0.026	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

DOCK11P1–BRCA

Open the BRCA breakdown →