DOC2GP

Across TCGA pan-cancer cohorts, DOC2GP RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated DOC2GP data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher DOC2GP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DOC2GP expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUSC show a favorable association.

KIRC, ACC, and KICH are the cancer types where DOC2GP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.515	0.716	<.001	120	view →
ACC	DFS	Median	II,III,IV	0.359	0.708	<.001	115	view →
KICH	DFS	Quartile	II,III,IV	0.059	1.000	<.001	95	view →
UVM	DFS	Tertile	All	0.428	0.882	<.001	90	view →
COAD	OS	Median	III,IV	0.407	0.654	.003	58	view →
SKCM	DFS	Quartile	III,IV	0.538	0.215	<.001	48	view →
PRAD	DFS	Median	All	0.832	0.933	<.001	34	view →
LUSC	OS	Median	III,IV	0.676	0.394	.005	31	view →
LGG	OS	Median	All	0.940	0.851	<.001	22	view →
STAD	OS	Tertile	II,III,IV	0.692	0.421	.018	21	view →
LAML	DFS	Tertile	All	0.262	0.478	.018	18	view →
CESC	OS	Tertile	All	0.720	0.458	.008	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

DOC2GP–KIRC (DFS)

Open the KIRC breakdown →