DNTTIP1

Across TCGA pan-cancer cohorts, DNTTIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated DNTTIP1 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher DNTTIP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated DNTTIP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, PDAC, and HNSC are the cancer types where DNTTIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	II,III,IV	0.927	0.467	.001	30	view →
PDAC	OS	Quartile	All	0.440	0.739	.012	10	view →
HNSC	DFS	Median	IV	0.328	0.889	.014	8	view →
UCEC	OS	Tertile	II,III,IV	0.617	1.000	.036	8	view →
LUAD	DFS	Tertile	III,IV	0.273	0.818	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

DNTTIP1–LSCC (OS)

Open the LSCC breakdown →