DNTTIP1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DNTTIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,443 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible DNTTIP1-associated GO terms across cancer lineages are Regulation of fibrinolysis, tRNA threonylcarbamoyladenosine metabolic process, and Spliceosomal tri-snRNP complex assembly. Each is linked with DNTTIP1 in more than 9 cancer types. Because this analysis shows association rather than direction, both DNTTIP1-to-partner and partner-to-DNTTIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibrinolysis grouped by DNTTIP1-low versus DNTTIP1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNTTIP1→partner) and Y-score (partner→DNTTIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCRegulation of fibrinolysis →+0.315+1.101.007.002310
SKINtRNA threonylcarbamoyladenosine metabolic process →+0.142+0.476.003.003310
SKINSpliceosomal tri-snRNP complex assembly →+0.077+0.500<.001<.001310
CNSMitotic centrosome separation →+0.148+0.636<.001.00339
SOFT_TISSUEVascular transport →-0.055-0.532<.001.00439
SOFT_TISSUETransport across blood-brain barrier →-0.055-0.532<.001.00439
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,443 associations by consensus.

Regulation of fibrinolysis by DNTTIP1 expression — LUNG_NSCLC_LUSC

Box plot of Regulation of fibrinolysis in DNTTIP1-low vs DNTTIP1-high samples in LUNG_NSCLC_LUSC.

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Exploration