DNTT

Across TCGA patient cohorts, DNTT RNA expression is significantly associated with the go_rna of many other GO terms, with 7,124 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DNTT-associated GO terms across cancer lineages are Viral gene expression, Negative regulation of leukocyte apoptotic process, and Aerobic respiration. Each is linked with DNTT in more than 12 cancer types. Because this analysis shows association rather than direction, both DNTT-to-partner and partner-to-DNTT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral gene expression grouped by DNTT-low versus DNTT-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DNTT→partner) and Y-score (partner→DNTT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Viral gene expression →	+0.059	+0.076	<.001	<.001	3	13
THYM	Negative regulation of leukocyte apoptotic process →	+0.054	+4.305	<.001	<.001	3	12
STAD	Aerobic respiration →	+0.060	+0.082	<.001	<.001	3	12
STAD	Mitochondrial depolarization →	+0.048	+0.075	<.001	<.001	3	12
STAD	Cellular response to alcohol →	+0.033	+0.072	<.001	<.001	3	12
ESCA	Cellular respiration →	+0.064	+0.114	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,124 associations by consensus.

Viral gene expression by DNTT expression — STAD

Explore this box plot interactively →