DNPH1

Across TCGA pan-cancer cohorts, DNPH1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DNPH1 data layer compared with 28 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DNPH1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DNPH1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where DNPH1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.775	0.397	<.001	99	view →
PDAC	OS	Median	All	0.910	0.787	.001	29	view →
HNSC	OS	Median	All	0.296	1.000	.003	21	view →
LSCC	OS	Tertile	All	0.960	0.767	.003	15	view →
COAD	DFS	Median	IV	0.493	0.944	.031	12	view →
LUAD	OS	Tertile	II,III,IV	0.760	0.457	.013	8	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DNPH1–CCRCC (DFS)

Open the CCRCC breakdown →