DNPEP

Across TCGA patient cohorts, DNPEP RNA expression is significantly associated with the protein abundance of many other proteins, with 8,497 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DNPEP-associated proteins across cancer lineages are AAMP, APP, and OTUD4_S893. Each is linked with DNPEP in more than 3 cancer types. Because this analysis shows association rather than direction, both DNPEP-to-partner and partner-to-DNPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNPEP versus AAMP in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNPEP→partner) and Y-score (partner→DNPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AAMP →	+0.453	+0.407	<.001	<.001	3	4
BRCA	APP →	-0.421	-0.524	.009	<.001	3	3
GBM	OTUD4_S893 →	+0.439	+0.331	<.001	.001	3	3
GBM	RRP8 →	+0.362	+0.406	<.001	<.001	3	3
COAD	SSB →	+0.280	+0.376	<.001	.007	3	3
LUAD	IFIH1 →	+0.453	+0.381	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,497 associations by consensus.

DNPEP vs AAMP — OV

Explore this scatter interactively →