DNPEP

Across TCGA patient cohorts, DNPEP protein abundance is significantly associated with the protein abundance of many other proteins, with 27,024 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible DNPEP-associated proteins across cancer lineages are ALDH9A1, HDHD2, and NHEJ1. Each is linked with DNPEP in more than 9 cancer types. Because this analysis shows association rather than direction, both DNPEP-to-partner and partner-to-DNPEP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DNPEP versus ALDH9A1 in UCEC, with a Pearson correlation of 0.51.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DNPEP→partner) and Y-score (partner→DNPEP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ALDH9A1 →	+0.474	+0.446	<.001	<.001	3	10
BRCA	HDHD2 →	+0.520	+0.466	<.001	<.001	3	9
OV	NHEJ1 →	+0.571	+0.397	<.001	<.001	3	9
COAD	CZIB →	+0.450	+0.288	.001	<.001	3	9
BRCA	ESD →	+0.517	+0.490	<.001	<.001	3	9
LUAD	APRT →	+0.509	+0.275	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 27,024 associations by consensus.

DNPEP vs ALDH9A1 — UCEC

Explore this scatter interactively →